Found 79 matching trials
Discontinuation of TyrosIne Kinase Inhibitors (TKI) in Chronic Myeloid Leukemia (CML) and Impact on the Immune System
PHASE3Tyrosine kinase inhibitors (TKI) have revolutionized the management and pro...
Status
Active Not Recruiting
Pioglitazone and Tyrosine Kinase Inhibitor in Treating Patients With Relapsed Chronic Myeloid Leukemia
PHASE2This phase II trial studies how well pioglitazone hydrochloride and tyrosin...
Location
Emory University/Winship Cancer Institute
Pegasys in Patients With Chronic Myeloid Leukemia (CML)
PHASE2The goal of this clinical research study is to learn if adding pegylated in...
Location
University of Texas MD Anderson Cancer Center
Precision Dosing of Tyrosine Kinase Inhibitors in CML Patients
N/AThe purpose of this prospective, single-institution observational study is ...
Persistence of MR3 in Chronic Myeloid Leukemia (CML) After a 2nd Stop of TKI Treatment
PHASE2This study will enroll CML patients who have failed a first TKI stopping at...
Location
Aarhus University Hospital
EPIgenetics and in Vivo Resistance of Chronic Myeloid Leukemia Stem Cells to Tyrosine Kinase Inhibitors
NAPrimary objective : To identify epigenetic dysregulations of in vivo TKI-re...
Location
CHU Annecy-Genevois
Treatment Free Remission (TFR) in CML Patients (CML-CP)Study
N/AImproving the quality of life and achieving Treatment-Free Remission(TFR) i...
Location
Multiple Locations
Open-label Study of Asciminib for CML-CP or CML-AP Patients With T315I Mutation Who Are Resistant, Intolerant or Ineligible to Ponatinib.
PHASE2The objective of this Phase II study is to assess the potential of ascimini...
Location
Novartis Investigative Site
Prospective Investigation of Dynamics of ABL Mutations in Imatinib Failed CML Patients Treated With Nilotinib
N/AThe purposes of this study are to investigate expression and frequency of A...
Location
Seoul St. Mary's Hospital
Interferon and GM-CSF Compared With Imatinib Mesylate and Vaccine Therapy in Patients With Chronic Phase CML on a TKI
PHASE2RATIONALE: Tyrosine kinase inhibitors may stop the growth of cancer cells b...
Location
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins